Co-encapsulation of Vitamin C and beta-Carotene in liposomes: Storage stability, antioxidant activity, and in vitro gastrointestinal digestion
文献类型： 外文期刊
作者： Liu, Xin 1 ; Wang, Peng 1 ; Zou, Yu-Xiao 2 ; Luo, Zhi-Gang 1 ; Tamer, Tamer Mahmoud 5 ;
作者机构： 1.South China Univ Technol, Sch Food Sci & Engn, Guangzhou 510640, Peoples R China
2.Guangdong Acad Agr Sci, Sericultural & Agrifood Res Inst GAAS, Guangzhou 510610, Peoples R China
3.South China Inst Collaborat Innovat, Dongguan 523808, Peoples R China
4.Overseas Expertise Intro Ctr Discipline Innovat F, Guangzhou 510640, Peoples R China
5.City Sci Res & Technol Applicat SRTA City, Polymer Mat Res Dept, Adv Technol & New Mat Res Inst, New Borg El Arab City 21934, Egypt
关键词： Vitamin C; beta-Carotene; Co-encapsulation; Liposomes; In vitro gastrointestinal digestion; Release kinetics
期刊名称：FOOD RESEARCH INTERNATIONAL （ 影响因子：6.475； 五年影响因子：6.508 ）
ISSN： 0963-9969
年卷期： 2020 年 136 卷
页码：
收录情况： SCI
摘要： Vitamin C (VC) and beta-Carotene (beta C) were selected to produce co-encapsulated liposomes using hydrophilic and hydrophobic cavities simultaneously by ethanol injection method. The results of liposomal structure characterized by particle size, polydispersity index, zeta-potential and transmission electron microscope showed that the microstructure of all liposomal samples was spherical without adhesion or break and the size of VC beta Cloaded liposome (L-VC-beta C) was bigger than VC-loaded liposome (L-VC) or beta C-loaded liposome (L-beta C). The encapsulation efficiency (EE) of VC in L-VC-beta C was significantly higher than that in L-VC, and the EE of beta C in L-VC-beta C had no significant change compared with that in L beta C. The free radical scavenging rate of L-VC-beta C was significantly higher than that of L beta C, while it had no significant change compared with that of L-VC. In addition, the storage stability of beta C in L-VC-beta C improved greatly compared with that in L-beta C. Furthermore, the zero order model was applied to understand the release kinetics of beta C from L-beta C and L-VC-beta C in the stomach, whereas the Korsmeyr-Peppas model was chosen to describe the release of beta C from two types of liposome in small intestine and their release mechanisms were mainly dominated by Fickian diffusion. It was significant to provide a new idea for using hydrophilic and hydrophobic cavities simultaneously in liposomes to design the multicomponent nutrient delivery system.
- 相关文献
作者其他论文 更多>>
-
Nitrogen-salt interaction in Pennisetum giganteum: Effects on soil, rhizosphere, and ion transport processes
作者：Wang, Peng;Zhang, Chen;Li, Wenyu;Guo, Junkang;Li, Yongtao;Pei, Xu;Li, Wenyan;Zhang, Zhen;Li, Yongtao;Woon, Kok Sin;Liu, Mengxue;Zhang, Zhen;Liu, Mengxue;Zhang, Zhen;Zhang, Kun;Woon, Kok Sin
关键词：Nitrogen-salt interaction; Pennisetum giganteum; Nitrogen transformation; Rhizosphere microbial community; Ion transport
-
Testicular tissue cryopreservation and transplantation as a strategy for feline conservation: a review of research advances
作者：Han, Zhiqiang;Liu, Xin;Du, Rui;Xu, Chao;Han, Zhiqiang;Wang, Haijun;Wang, Haijun;Qazi, Izhar Hyder;Qazi, Izhar Hyder;Wang, Luyao;Dai, Xiangpeng;Wang, Luyao;Dai, Xiangpeng
关键词：big cats; fertility; preservation; sperm; vitrification
-
Zearalenone Decreases Food Intake by Disrupting the Gut-Liver-Hypothalamus Axis Signaling via Bile Acids
作者：Yuan, Peiqiang;Ma, Rongman;Huang, Jiancai;Wen, Hongmei;Huang, Lingjie;Li, Hua;Feng, Bin;Zhang, Xiaoling;Lin, Yan;Xu, Shengyu;Li, Jian;Zhuo, Yong;Hua, Lun;Che, Lianqiang;Wu, De;Fang, Zhengfeng;Yuan, Peiqiang;Hu, Liang;Li, Ran;Huang, Lingjie;Chen, Hong;Liu, Yuntao;Fang, Zhengfeng;Wang, Peng;Lin, Sen
关键词：zearalenone; bile acid metabolism; toxicity; farnesoid X receptor; food intake
-
Biogenic manganese oxides promote metal(loid) remediation by shaping microbial communities in biological aqua crust
作者：Wang, Guobao;Feng, Zekai;Chen, Daijie;Chen, Chiyu;Ao, Ming;Chen, Ziwu;Yang, Wenjun;Li, Dantong;Chao, Yuanqing;Wang, Peng;Tang, Yetao;Qiu, Rongliang;Wang, Shizhong;Wang, Guobao;Yin, Xiuran;Zhao, Nan;Yuan, Yongqiang;Liu, Chong;Chen, Lei;Morel, Jean Louis;Qiu, Rongliang
关键词：Biological aqua crust; Metal(loid) bioremediation; Biogenic Mn oxide minerals; Aggregate formation; Metagenomics
-
The structural characteristics, biological activities and mechanisms of bioactive brown seaweed polysaccharides: A review
作者：Zhou, Qing-Ling;Wang, Zhuo;Chen, Wen-Ting;Liu, Xiao-Fei;Cheong, Kit-Leong;Zhong, Sai-Yi;Li, Rui;Zou, Yu-Xiao;Zhong, Sai-Yi;Li, Rui
关键词：Brown seaweed; Polysaccharide; Action mechanism; Fucoidan; Alginate; Laminarin
-
Andrographolide protects against the intestinal barrier dysfunction and inflammatory response through modulating ETEC virulence factors in a mouse model of diarrhea
作者：Wang, Peng;Fan, Aoshuang;Zhao, Jinduo;Liu, Yangming;Feng, Lin;Xia, Fangyu;Tian, Yuting;Gan, Liping;Qiao, Hanzhen;Duan, Erzhen;Huang, Jin;Wang, Jinrong;Lin, Sen
关键词：Enterotoxigenic Escherichia coli; Intestinal barrier; Inflammatory response; Andrographolide; Virulence factors
-
Bile acids and their receptors in regulation of gut health and diseases
作者：Lin, Sen;Wu, De;Fang, Zhengfeng;Lin, Sen;Tang, Cuiming;Wang, Zhenjiang;Chen, Lian;Luo, Guoqing;Wang, Sutian;Wang, Peng;Chen, Hong;Liu, Yuntao;Feng, Bin;Fang, Zhengfeng;Burrin, Douglas G.
关键词：Bile acids; FXR; GPBAR1; Inflammatory bowel diseases; Colorectal cancers
