您好，欢迎访问广东省农业科学院 机构知识库！
广东省农业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Efficacy of commercial polyvalent avian infectious bronchitis vaccines against Chinese QX-like and TW-like strain via different vaccination strategies

文献类型： 外文期刊

作者： Shao, Guanming 1 ; Chen, Tong 1 ; Feng, Keyu 1 ; Zhao, Qiqi 1 ; Zhang, Xinheng 1 ; Li, Hongxin 1 ; Lin, Wencheng 1 ; Xie, 1 ;

作者机构： 1.South China Agr Univ, Coll Anim Sci, Guangzhou 510642, Peoples R China

2.Minist Agr, Guangdong Prov Key Lab Agroanim Genom & Mol Breed, Guangzhou 510642, Peoples R China

3.Minist Agr, Key Lab Chicken Genet Breeding & Reprod, Guangzhou 510642, Peoples R China

4.Key Lab Anim Hlth Aquaculture & Environm Control, Guangzhou 510642, Peoples R China

5.Guangdong Anim Virus Vector Vaccine Engn Res Ctr, Guangzhou 510642, Peoples R China

6.South China Agr Univ, Coll Anim Sci, Guangzhou 510640, Peoples R China

7.South China Collaborat Innovat Ctr Poultry Dis Co, Guangzhou 510640, Peoples R China

关键词： infectious bronchitis virus; polyvalent vaccine; vaccination strategy; QX-like; TW-like

期刊名称：POULTRY SCIENCE （ 影响因子：3.352； 五年影响因子：3.679 ）

ISSN：

年卷期： 2020 年 99 卷 10 期

页码：

收录情况： SCI

摘要： The infectious bronchitis virus (IBV) is an acute and highly contagious disease, which affects chickens of all ages. Vaccination is the most important way to control this disease. Nevertheless, novel variant strains are constantly reported because of the lack of proofreading capabilities of RNA polymerase and high frequency of homologous RNA recombination. Cross-protection studies has demonstrated that the vaccines could provide great protective effects against viruses of same serotype or genotype. However, the protective effect of different commercial vaccines and vaccine combinations against the prevalent IBVstrains in China has rarely been studied. Owing to the multiple genotype or serotype IBV strains prevalence in China, the polyvalent vaccines and their composition were used to expanding the protection spectrum of vaccine in practical application. To evaluate the protection of Chinese commercial IBV polyvalent vaccines against prevalent strains (QX-like and TWI-like), an immune challenge test was conducted. Four polyvalent vaccines, containing 4/91, H120, YX10p90, LDT3-A, and 28/86, were combined to form 8 vaccination strategies, almost all of which could provide more than 70% protection effects against challenge with QX-like strain. Particularly, the best protection rate (93%) was generated by administration the polyvalent vaccine C (H120 1 28/86 1 4/91) at 1 D of age and the polyvalent vaccine B (H120 1 4/91 1 YX10p90) at 10 D of age. However, all the vaccination strategies in this study cannot provide great protective effects against TW-like strain, and more vaccines should be included in studies to expand the protection spectrum of vaccine. Therefore, for the newly emerging IBV strains, immunization with polyvalent vaccines via different vaccination strategies could be used to control the prevalence of IBV in a short time, whereas developing the homologous vaccines was not always necessary.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：广东省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台