文献类型： 外文期刊
作者： Zhao, Huan 1 ; Duan, Rui-Jun 1 ; Kong, Chui-Hao 2 ; Dai, Hao-Fu 1 ; Mei, Wen-Li 1 ; Xu, Feng-Qing 2 ; Huang, Sheng-Zhuo 1 ;
作者机构： 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Key Lab Res & Dev Nat Prod Li Folk Med Hainan Prov, Haikou 571101, Peoples R China
2.Anhui Univ Chinese Med, Sch Pharm, Hefei 230012, Peoples R China
3.Chinese Acad Trop Agr Sci, Hainan Inst Trop Agr Resources, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China
4.Anhui Prov Key Lab New Mfg Technol Tradit Chinese, Hefei 230012, Peoples R China
5.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, 4 Xueyuan Rd, Haikou 571101, Hainan, Peoples R China
关键词： Euphorbia atoto; euphorbiaceae; trachylobane-type diterpenoids; anti-inflammatory activities
期刊名称：JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH （ 影响因子：1.7； 五年影响因子：1.7 ）
ISSN： 1028-6020
年卷期： 2023 年
页码：
收录情况： SCI
摘要： Two new rare trachylobane euphoratones A-B (1-2), together with five known diterpenoids (compounds 3-7), were isolated from the aerial parts of Euphorbia atoto. Their structures were unambiguously elucidated through HRESIMS, 1D and 2D NMR spectral analysis. Compounds 1, 3, 4 and 7 showed weak anti-inflammatory activities (IC50 77.49 & PLUSMN; 6.34, 41.61 & PLUSMN; 14.49, 16.00 & PLUSMN; 1.71 and 33.41 & PLUSMN; 4.52 & mu;M, respectively), compared to the positive control quercetin (IC50 15.23 & PLUSMN; 0.65 & mu;M).
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