您好，欢迎访问广东省农业科学院 机构知识库！
广东省农业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Anandins A and B, Two Rare Steroidal Alkaloids from a Marine Streptomyces anandii H41-59

文献类型： 外文期刊

作者： Zhang, Yang-Mei 1 ; Liu, Bai-Lian 1 ; Zheng, Xin-Heng 1 ; Huang, Xiao-Jun 1 ; Li, Hong-Yu 1 ; Zhang, Ying 1 ; Zhang, T 1 ;

作者机构： 1.Jinan Univ, Guangdong Prov Key Lab Pharmacodynam Constituents, Inst Tradit Chinese Med & Nat Prod, Coll Pharm, Guangzhou 510632, Guangdong, Peoples R China

2.Jinan Univ, Guangdong Prov Key Lab Pharmacodynam Constituents, Inst Tradit Chinese

关键词： Streptomyces anandii;anandins A and B;steroidal alkaloids;cytotoxicity

期刊名称：MARINE DRUGS （ 影响因子：5.118； 五年影响因子：5.951 ）

ISSN： 1660-3397

年卷期： 2017 年 15 卷 11 期

页码：

收录情况： SCI

摘要： Anandins A (1) and B (2), two rare steroidal alkaloids, were isolated from the fermentative broth of a marine actinobacteria Streptomyces anandii H41-59. The gross structures of the two alkaloids were elucidated by spectroscopic methods including HR-ESI-MS, and NMR. Their absolute configurations were confirmed by single-crystal X-ray diffraction analysis and comparison of their experimental and calculated electronic circular dichroism spectra, respectively. Anandin A exhibited a moderate inhibitory effect against three human cancer cell lines MCF-7, SF-268, and NCI-H460 with IC50 values of 7.5, 7.9, 7.8 g/mL, respectively.

  • 相关文献

[1]Ergosterols from the Culture Broth of Marine Streptomyces anandii H41-59. Zhang, Yang-Mei,Li, Hong-Yu,Hu, Chen,Zhang, Ying,Zhou, Guang-Xiong,Sheng, Hui-Fan,Lin, Bi-Run. 2016

[2]New Xanthone from the Pericarp of Garcinia mangostana. Fu, Manqin,Xu, Yujuan,Wu, Jijun,Chen, Yulong,Yu, Yuanshan,Xiao, Gengsheng,Qiu, Samuel X.. 2013

[3]Neoantimycins A and B, Two Unusual Benzamido Nine-Membered Dilactones from Marine-Derived Streptomyces antibioticus H12-15. Hu, Chen,Zhou, Shi-Wen,Chen, Fang,Zheng, Xin-Heng,Zhou, Guang-Xiong,Shen, Hui-Fang,Lin, Bi-Run.

[4]Overexpression of SIRT6 in Porcine Fetal Fibroblasts Attenuates Cytotoxicity and Premature Senescence Caused by D-Galactose and Tert-Butylhydroperoxide. Xie, Xiaoxian,Zhang, Hao,Wang, Liangliang,Zhang, Ailing,Li, Jiaqi,Xie, Xiaoxian,Zhang, Hao,Wang, Liangliang,Zhang, Ailing,Li, Jiaqi,Gao, Ping,Xie, Shuihua.

作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：广东省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台