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Three new flavanoids from artificially induced dragon's blood of Dracaena cambodiana

文献类型: 外文期刊

作者: Li, Fei-Xiang 1 ; Wang, Hui 1 ; Gai, Cui-Juan 1 ; Chen, Hui-Qin 1 ; Li, Wei 1 ; Mei, Wen-Li 1 ; Dai, Hao-Fu 2 ;

作者机构: 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Key Lab Biol & Genet Resources Trop Crops, Minist Agr, Haikou 571101, Hainan, Peoples R China

2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Key Lab Biol & Genet Resources Trop Crops, Minis

关键词: Artificially induced dragon's blood;flavanoids;Dracaena cambodiana;cytotoxicity;AChE

期刊名称:JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH ( 影响因子:1.569; 五年影响因子:1.598 )

ISSN: 1028-6020

年卷期: 2018 年 20 卷 1 期

页码:

收录情况: SCI

摘要: Three new flavanoids, (2R)-7,4'-dihydroxy-8-methylflavan (1), (2R)-7,4'-dihydroxy-6-methylflavan (2), and (3R)-7,3',4'-trihydroxyhomoisoflavan (3), together with seven known compounds (4-10), were isolated from artificially induced dragon's blood of Dracaena cambodiana, and their structures were determined based on HR-ESI-MS and extensive spectroscopic techniques (UV, IR, 1D-, and 2D-NMR). Compound 2 exhibited weak cytotoxicity against BEL-7402 cells line with the IC50 value of 39.2 mu M. In addition, compound 3 showed significant acetylcholinesterase (AChE) inhibitory activity. GRAPHICS

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