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Metabolites from endophytic fungus S20 of Cephalotaxus hainanensis

文献类型： 外文期刊

作者： Dai, Wen-Jun 1 ; Wu, Jiao 1 ; Han, Zhuang 1 ; Mei, Wen-Li 1 ; Dai, Hao-Fu 1 ;

作者机构： 1.Chinese Acad Trop Agr Sci, Minist Agr, Inst Trop Biosci & Biotechnol, Key Lab Trop Crop Biotechnol, Haikou 571101, Peoples R China

关键词： Cephalotaxus hainanensis Li;endophytic fungus;acetogenins;antibacterial activity

期刊名称：JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH （ 影响因子：1.569； 五年影响因子：1.598 ）

ISSN： 1028-6020

年卷期： 2009 年 11 卷 8 期

页码：

收录情况： SCI

摘要： Three new C-methylated acetogenins, (2E,6Z)-9,10-dihydroxy-4-hydroxymethyl-2,6-decadiene (1), (2E,6Z)-8,9,10-trihydroxy-4-hydroxymethyl-2,6-decadiene (2), and (2E,6Z)-9-hydroxy-4-hydroxymethyl-2,6-nonadiene (3), together with two known compounds, p-hydroxybenzyl alcohol (4) and indolyl-3-carboxylic acid (5), were isolated from endophytic fungus S20 of Cephalotaxus hainanensis Li. Their structures were determined based on HR-ESI-MS and spectroscopic techniques (IR, UV, 1D, and 2D NMR). Compound 5 showed inhibitory effects on Staphylococcus aureus and methicillin-resistant S. aureus by the filter paper disc agar diffusion method.

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