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A New Cyclic Peptide from Betel Nut Endophytic Fungus Alternaria sp. RW-AL

文献类型: 外文期刊

作者: Ruan, Wu 1 ; Ma, Qing-Yun 1 ; Guo, Jiao-Cen 1 ; Xie, Qing-Yi 1 ; Yang, Li 1 ; Dai, Hao-Fu 1 ; Wu, You-Geng 3 ; Zhao, You-Xing 1 ;

作者机构: 1.CATAS, Inst Trop Biosci & Biotechnol, Haikou Key Lab Res & Utilizat Trop Nat Prod, Haikou 571101, Peoples R China

2.CATAS, Inst Trop Biosci & Biotechnol, Natl Key Lab Trop Crop Breeding, Haikou 571101, Peoples R China

3.Hainan Univ, Sanya Inst Breeding & Multiplicat, Sch Breeding & Multiplicat, Sanya 572025, Hainan, Peoples R China

关键词: Endophytic fungus; Alternaria sp.; cyclic peptide; antibacterial activities

期刊名称:CHEMISTRY OF NATURAL COMPOUNDS ( 影响因子:0.8; 五年影响因子:0.8 )

ISSN: 0009-3130

年卷期: 2024 年

页码:

收录情况: SCI

摘要: A new cyclic peptide alternarin A (1), along with seven known compounds, alternariol (2), sulfated derivative of alternariol (3), alternariol methyl ether (4), altenuene (5), 2,5-dimethyl-7-hydroxychromone (6), diaporthein A (7), isopterocarpolone (8), were isolated from the betel nut endophytic fungus Alternaria sp. RW-AL. The structure of 1 was elucidated by 1D and 2D NMR spectra as well as HR-ESI-MS analysis. Compounds 1, 4, and 5 showed definite antibacterial activities against Staphylococcus aureus ATCC 6538 and Bacillus subtilis ATCC 6633.

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