文献类型： 外文期刊
作者： Pan, Jie-Ming 1 ; Chen, Hui-Qin 1 ; Wang, Hao 1 ; Yang, Li 1 ; Cai, Cai-Hong 1 ; Mi, Cheng-Neng 1 ; Dai, Hao-Fu 1 ; Tan, 1 ;
作者机构： 1.Chinese Acad Trop Agr Sci, Hainan Key Lab Res & Dev Nat Prod Li Folk Med, Inst Trop Biosci & Biotechnol, Haikou 571101, Hainan, Peoples R China
2.Hainan Univ, Inst Trop Agr & Forestry, Haikou 570228, Hainan, Peoples R China
3.Yulin Normal Univ, Coll Biol & Pharm, Yulin 537000, Peoples R China
关键词： Cycloheximide derivative; Streptomyces sp; antifungal activity
期刊名称：JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH （ 影响因子：1.569； 五年影响因子：1.598 ）
ISSN： 1028-6020
年卷期：
页码：
收录情况： SCI
摘要： A couple of new cycloheximide epimers, 13(alpha)-acetoxy-anhydroisoheximide (1) and 13(beta)-acetoxy-anhydroisoheximide (2), together with six known compounds (3-8), were obtained from the cultures of Streptomyces sp. YG7. The structures were elucidated based on a comprehensive spectroscopic data analysis including 1D and 2D NMR, as well as HRESIMS, and by comparison with the literature. The X-ray crystal analysis of 1 further confirmed the structure. All the compounds were tested for antifungal activity. Compounds 1, 2 and 5-8 showed moderate Canidia albicans inhibitory activity, while 5 and 6 presented moderate Pyricularia oryzae inhibitory activity. [GRAPHICS] .
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