A phytochemical investigation of Stemona parviflora roots reveals several compounds with nematocidal activity
文献类型： 外文期刊
作者： Huang, Sheng-Zhuo 1 ; Kong, Fan-Dong 1 ; Chen, Gao; Cai, Xiang-Hai; Zhou, Li-Man 1 ; Ma, Qing-Yun 1 ; Wang, Qi 1 ;
作者机构： 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Hainan Key Lab Res & Dev Nat Prod Li Folk Med, Haikou 571101, Hainan, Peoples R China
2.Chinese A
关键词： Stemona parviflora; Stemonaceae; Phenanthrene; Stilbene; Nematocidal activity
期刊名称：PHYTOCHEMISTRY （ 影响因子：4.072； 五年影响因子：4.132 ）
ISSN： 0031-9422
年卷期： 2019 年 159 卷
页码：
收录情况： SCI
摘要： Twelve undescribed compounds including six phenanthrene derivatives (parviphenanthrines A-F), two stilbene derivatives (parvistilbines A-B), three esters (parviesters A-C), and one sesquiterpenoid (parvidiol A) were isolated from the roots of Stemona parviflora, together with twenty-two known ones. The structures of the undescribed compounds were elucidated based on the analyses of their spectroscopic data. The absolute configuration of parviphenanthrine A was determined by the quantum ECD calculations. Parviphenanthrines A and E, stemanthrene A, stilbostenin E, 4-hydroxy-benzenepropanol-alpha-benzoate, and (E)-4-hydroxycinnamic acid methyl ester showed nematocidal activity against Meloidogyne incognita with IC50 values of 14.02 +/- 0.32, 2.51 +/- 0.13, 17.10 +/- 0.65, 2.05 +/- 0.07, 4.22 +/- 0.31, and 1.07 +/- 0.05 mu m, respectively.
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