文献类型： 外文期刊
作者： Su, Xin 1 ; Cai, Cai-Hong 1 ; Dong, Wen-Hua 1 ; Gai, Cui-Juan 1 ; Wang, Ya-Li 1 ; Mei, Wen-Li 1 ; Xu, Xing-Lian 3 ; Dai, Hao-Fu 1 ; Chen, Hui-Qin 1 ;
作者机构： 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Hainan Engn Res Ctr Agarwood, Haikou 571101, Peoples R China
2.Hainan Inst Trop Agr Resources, Haikou 571101, Hainan, Peoples R China
3.Nanjing Agr Univ, Coll Food Sci & Technol, Nanjing 210000, Peoples R China
关键词： Chong-lou' agarwood; Aquilaria sinensis; 2-(2-phenylethyl)chromones; Cytotoxicity
期刊名称：PHYTOCHEMISTRY LETTERS （ 影响因子：1.873； 五年影响因子：1.875 ）
ISSN： 1874-3900
年卷期： 2022 年 51 卷
页码：
收录情况： SCI
摘要： Three new 2-(2-phenylethyl)chromones (1, 2 and 3), together with four known analogues 4-7 were isolated from "Chong-lou' agarwood originating from Aquilaria sinensis for the first time. Their new structures were elucidated on the basis of spectroscopic techniques (UV, IR, MS, 1D and 2D NMR), as well as by comparison with the literature data. Compounds 6 and 7 exhibited significant cytotoxicity against human cancer cell line K562 with IC50 values of 19.79 +/- 0.03 and 21.39 +/- 0.05 mu M, respectively.
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