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Two new strophanthidol cardenolides from the seeds of Antiaris toxicaria

文献类型: 外文期刊

作者: Zuo, Wen-Jian 1 ; Dong, Wen-Hua 1 ; Jing-Chen 2 ; Zhao, You-Xing 1 ; Chen, Hui-Qin 1 ; Mei, Wen-Li 1 ; Dai, Hao-Fu 1 ;

作者机构: 1.Chinese Acad Trop Agr Sci, Key Lab Biol & Genet Resources Trop Crops, Minist Agr, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China

2.Ningxia Med Univ, Ningxia Res Ctr Modern Hui Med Engn & Technol, Sch Pharm, Yinchuan 750004, Peoples R China

关键词: Antiaris toxicaria;Seed;Cardenolide;Cytotoxicity;Strophanthidol

期刊名称:PHYTOCHEMISTRY LETTERS ( 影响因子:1.679; 五年影响因子:1.861 )

ISSN:

年卷期:

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收录情况: SCI

摘要: Two new strophanthidol cardenolides, toxicarioside N (1) and toxicarioside 0 (2), together with three known ones, were isolated from the seeds of Antiaris toxicaria. The structures of the new compounds were identified as strophanthidol-3-O-beta-d-glucopyranosyl-(l -> 4)-6-deoxy-0-d-al!opyranoside(l)and strophanthidol-3-O-beta-d-glucopyranoside (2), respectively. The cytotoxic test showed that compounds 1 and 2 exhibited significant cytotoxicity against SMMC-7721 and K562.

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