Identification of a Chicken Anemia Virus Variant-Related Gyrovirus in Stray Cats in China, 2012
文献类型： 外文期刊
作者： Zhang, Xinheng 1 ; Liu, Yuanjia 2 ; Ji, Jun 1 ; Chen, Feng 1 ; Sun, Baoli 1 ; Xue, Chunyi 3 ; Ma, Jingyun 1 ; Bi, Yingzuo 1 ;
作者机构： 1.South China Agr Univ, Coll Anim Sci, Guangzhou 510642, Guangdong, Peoples R China
2.South China Agr Univ, Coll Vet Med, Guangzhou 510642, Guangdong, Peoples R China
3.Sun Yat Sen Univ, Coll Life Sci, State Key Lab Biocontrol, Guangzhou 510006, Guangdong, Peoples R China
4.Minist Agr, Key Lab Chicken Genet, Guangzhou 510642, Guangdong, Peoples R China
期刊名称：BIOMED RESEARCH INTERNATIONAL （ 影响因子：3.411； 五年影响因子：3.62 ）
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收录情况： SCI
摘要： The chicken anemia virus (CAV), is a known member of the genus Gyrovirus and was first isolated from chickens in Japan in 1979. Some reports have also demonstrated that CAV can be identified in human stool specimens. In this study, a variant of CAV was detected using PCR with CAV-based primers in fecal samples of stray cats. The genome of CAV variant was sequenced and the results suggest that it could be a recombinant viral strain from parental CAV strains JQ690762 and AF311900. Recombination is an important evolutionary mechanism that contributes to genetic diversification. These findings indicate that CAV variant might have originated from CAV-infected chickens. The epidemiology and pathogenesis of this novel virus remains to be elucidated. This study underscores the importance of CAV surveillance and it presents the first evidence suggesting the possibility of CAV homologous recombination in cat.
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