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Indole Alkaloids from Kopsia hainanensis and Evaluation of Their Antimicrobial Activity

文献类型： 外文期刊

作者： Yang, Yong 1 ; Zuo, Wen-Jian 1 ; Zhao, You-Xing 1 ; Dong, Wen-Hua 1 ; Mei, Wen-Li 1 ; Dai, Hao-Fu 1 ;

作者机构： 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Hainan Key Lab Res & Dev Nat Prod Li Folk Med, Haikou 571101, Hainan, Peoples R China

2.Hainan Univ, Hort & Garden Coll, Haikou, Hainan, Peoples R China

关键词： Kopsia hainanensis;Apocynaceae;indole alkaloids;antimicrobial activity

期刊名称：PLANTA MEDICA （ 影响因子：3.352； 五年影响因子：3.4 ）

ISSN：

年卷期：

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收录情况： SCI

摘要： Three new indole alkaloids, named kopsihainin D (1), kopsihainin E (2), and kopsihainin F (3), along with nine known compounds (4-12) were isolated from the twigs of Kopsia hainanensis. The structures of the new compounds were elucidated by spectroscopic methods including HRESIMS, UV, IR, and NMR. Compounds 1-3 and 5 showed inhibitory activity against Staphylococcus aureus with an antibacterial circle diameter of 11.2, 9.1, 10.3 and 9.7 mm, respectively.

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