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A novel rosamine-based fluorescent probe for bisulfite in aqueous solution

文献类型: 外文期刊

作者: Zhang, Di 1 ; Liu Wenya 2 ; Chen, Keke 2 ; Cheng, Junye 2 ; Zhao, Yufen 2 ; Ye, Yong 2 ;

作者机构: 1.Henan Acad Agr Sci, Inst Agr Qual Stand & Testing Technol, Zhengzhou, Peoples R China

2.Zhengzhou Univ, Coll Chem & Mol Engn, Phosphorus Chem Engn Res Ctr Henan Prov, Zhengzhou, Peoples R China

3.Tsinghua Univ, Dept Chem, Minist Educ, Key Lab Bioorgan Phosphorus Chem & Chem Biol, Beijing, Peoples R China

期刊名称:RSC ADVANCES ( 影响因子:3.361; 五年影响因子:3.39 )

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收录情况: SCI

摘要: A new rosamine-based fluorescent probe (RosCHO)for bisulfite was obtained by one pot reaction of p-phthalaldehyde and 3-(diethylamino) phenol, which showed excellent selectivity, high sensitivity and a rapid response toward bisulfite in aqueous solution. Upon the addition of HSO3-, the aldehyde moiety in probe RosCHO formed a hydrogen sulfite-dependent adduct product, leading to fluorescence enhancement due to the different ICT process. The detection limit for bisulfite was as low as 7 x 10(-8) M, and fluorescence imaging of bisulfite in MCF-7 cells demonstrated its value to practical application in biological systems.

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