文献类型： 外文期刊
作者： He, Dan 1 ; Ma, Qing-Yun 2 ; Yang, Li 2 ; Xie, Qing-Yi 2 ; Zhu, Hong-Juan 1 ; Dai, Hao-Fu 2 ; Wu, You-Gen 1 ; Yang, Dong-Mei 1 ; Zhao, You -Xing 2 ;
作者机构： 1.Hainan Univ, Sanya Nanfan Res Inst, Sanya 572025, Peoples R China
2.CATAS & Hainan Acad Trop Agr Resource, Inst Trop Biosci & Biotechnol, Haikou Key Lab Res & Utilizat Trop Nat Prod, Haikou 571101, Peoples R China
3.Hainan Univ, Sch Hort, Key Lab Qual Regulat Trop Hort Crops Hainan Prov, Haikou 570228, Peoples R China
4.Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China
关键词： Acrostichum aureum; Endophytic fungi; Colletotrichum sp; Indole alkaloids; Colletotryptin
期刊名称：PHYTOCHEMISTRY LETTERS （ 影响因子：1.7； 五年影响因子：1.8 ）
ISSN： 1874-3900
年卷期： 2023 年 54 卷
页码：
收录情况： SCI
摘要： Two new indole alkaloids, colletotryptins G (1) and H (2), along with four known alkaloids (3-6), were isolated from an endophytic fungus Colletotrichum sp. HD-1 (Melanconiaceae) derived from the mangrove plant Acros-tichum aureum (Pteridaceae). The structures of new compounds were elucidated by comprehensive analysis of their UV, HRESIMS, and NMR data. All the isolates were evaluated for their alpha-glucosidase and acetylcholines-terase inhibitory, antibacterial, and antifungal activities. Only compound 2 showed stronger inhibitory activity against alpha-glucosidase with IC50 value of 133.4 mu M than that of the positive control acarbose (319.8 mu M).
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