您好,欢迎访问中国热带农业科学院 机构知识库!

Two new indole alkaloids isolated from a mangrove-derived fungus Colletotrichum sp. HD-1

文献类型: 外文期刊

作者: He, Dan 1 ; Ma, Qing-Yun 2 ; Yang, Li 2 ; Xie, Qing-Yi 2 ; Zhu, Hong-Juan 1 ; Dai, Hao-Fu 2 ; Wu, You-Gen 1 ; Yang, Dong-Mei 1 ; Zhao, You -Xing 2 ;

作者机构: 1.Hainan Univ, Sanya Nanfan Res Inst, Sanya 572025, Peoples R China

2.CATAS & Hainan Acad Trop Agr Resource, Inst Trop Biosci & Biotechnol, Haikou Key Lab Res & Utilizat Trop Nat Prod, Haikou 571101, Peoples R China

3.Hainan Univ, Sch Hort, Key Lab Qual Regulat Trop Hort Crops Hainan Prov, Haikou 570228, Peoples R China

4.Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China

关键词: Acrostichum aureum; Endophytic fungi; Colletotrichum sp; Indole alkaloids; Colletotryptin

期刊名称:PHYTOCHEMISTRY LETTERS ( 影响因子:1.7; 五年影响因子:1.8 )

ISSN: 1874-3900

年卷期: 2023 年 54 卷

页码:

收录情况: SCI

摘要: Two new indole alkaloids, colletotryptins G (1) and H (2), along with four known alkaloids (3-6), were isolated from an endophytic fungus Colletotrichum sp. HD-1 (Melanconiaceae) derived from the mangrove plant Acros-tichum aureum (Pteridaceae). The structures of new compounds were elucidated by comprehensive analysis of their UV, HRESIMS, and NMR data. All the isolates were evaluated for their alpha-glucosidase and acetylcholines-terase inhibitory, antibacterial, and antifungal activities. Only compound 2 showed stronger inhibitory activity against alpha-glucosidase with IC50 value of 133.4 mu M than that of the positive control acarbose (319.8 mu M).

  • 相关文献
作者其他论文 更多>>