文献类型： 外文期刊
作者： An, Chang-Liang 1 ; Ma, Qing-Yun 1 ; Xie, Qing-Yi 1 ; Yang, Li 1 ; Yuan, Jing-Zhe 1 ; Dai, Hao-Fu 1 ; Zhao, You-Xing 1 ;
作者机构： 1.CATAS, Inst Trop Biosci & Biotechnol, Hainan Inst Trop Agr Resources, Haikou Key Lab Res & Utilizat Trop Nat Prod, Haikou 571101, Peoples R China
关键词： Marine sediment-derived fungi; Acremonium sp.; secondary metabolites; antioxidant and antibacterial activities
期刊名称：JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH （ 影响因子：1.7； 五年影响因子：1.7 ）
ISSN： 1028-6020
年卷期： 2023 年
页码：
收录情况： SCI
摘要： Two new compounds named 3(S)-hydroxy-1-(2,4,5-trihydroxy-3,6- dimethylphenyl)-hex-4E-en-1-one (1) and acremonilactone (2), together with nine known compounds (3-11), were isolated from the fermentation broth of Acremonium sp. associated with marine sediments collected from South China Sea. NMR and HRESIMS spectroscopic analysis elucidated the structure of two new compounds. Compound 2 had characteristic rotary gate shape skeleton with a six-membered lactone. Compounds 1 and 9 showed DPPH radical scavenging activity with inhibition rates of 96.50 and 85.95% at the concentration of 0.5 mg/ml, respectively. Moreover, compounds 4, 6 and 11 showed definite antibacterial activity against Staphylococcus aureus ATCC 6538.
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