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Two new triterpenoid saponins from Bupleurum marginatum Wall. ex DC

文献类型: 外文期刊

作者: Luo, Ke 1 ; Dai, Rong-Ji 1 ; Wang, Zhi 1 ; Zeng, Yan-Bo 2 ; Deng, Yu-Lin 1 ; Lv, Fang 1 ;

作者机构: 1.Beijing Inst Technol, Sch Life Sci, Beijing Key Labrotary Separat & Anal Biomed & Pha, Beijing, Peoples R China

2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Hainan Prov Key Lab Funct Components Res & Utiliz, Haikou, Hainan, Peoples R China

关键词: Bupleurum marginatum Wall; ex DC; cytotoxicity; medicinal plant; triterpenoid saponins

期刊名称:NATURAL PRODUCT RESEARCH ( 影响因子:2.488; 五年影响因子:2.51 )

ISSN: 1478-6419

年卷期:

页码:

收录情况: SCI

摘要: Two new triterpenoid saponins (1 and 2), together with two known saponins (3 and 4) were isolated from Bupleurum marginatum Wall. ex DC. Their structures were elucidated by the comprehensive spectroscopic analysis. Compounds 1 and 2 represented the rare example of an oleanane-type triterpenoid with two sugar moieties at C-3 and C-28. The cytotoxic activity of four compounds was evaluated against normal heptocell BRL-3A in vitro.

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