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New sesquiterpenoids bearing 11-methyl ester group of agarwood

文献类型: 外文期刊

作者: Li, Wei 1 ; Yang, Yi-Ling 2 ; Yang, Li 1 ; Wang, Hao 1 ; Dong, Wen-Hua 1 ; Cai, Cai-Hong 1 ; Yuan, Jing-Zhe 1 ; Jiang, Be 1 ;

作者机构: 1.Chinese Acad Trop Agr Sci, Hainan Engn Res Ctr Agarwood, Inst Trop Biosci & Biotechnol, Haikou 571101, Hainan, Peoples R China

2.Dali Univ, Pharm & Chem Coll, Dali 671000, Peoples R China

关键词: Agarwood; Sesquiterpenoid; Acetylcholinesterase inhibitory activity

期刊名称:FITOTERAPIA ( 影响因子:2.882; 五年影响因子:3.202 )

ISSN: 0367-326X

年卷期: 2020 年 143 卷

页码:

收录情况: SCI

摘要: Five new sesquiterpenoids (1-5), together with a known compound 6 was isolated from ethyl ether extract of agarwood. Their structures were elucidated on the basis of spectroscopic techniques (UV, IR, MS, 1D and 2D NMR), as well as by comparison with literature data. Compound 5 exhibited inhibitory activity against acetylcholinesterase with inhibition ratio of 48.33 +/- 0.17% at the concentration of 50 mu g/mL.

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