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A novel degraded sesquiterpene from the fresh stem of Aquilaria sinensis

文献类型： 外文期刊

作者： Peng, Ke 1 ; Mei, Wen-Li 2 ; Zhao, You-Xing 2 ; Tan, Le-He 1 ; Wang, Qing-Huang 1 ; Dai, Hao-Fu 1 ;

作者机构： 1.Chinese Acad Trop Agr Sci, Natl Ctr Important Trop Crops Engn & Technol Res, Danzhou 571737, Peoples R China

2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Hainan Key Lab Res & Dev Nat Prod Li Folk Med, Haikou 571101, Peoples R China

3.Luzhou Monitoring Stn Environm Prote

关键词： Aquilaria sinensis;aquilarin B;cytotoxic activity

期刊名称：JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH （ 影响因子：1.569； 五年影响因子：1.598 ）

ISSN： 1028-6020

年卷期： 2011 年 13 卷 10 期

页码：

收录情况： SCI

摘要： A novel degraded sesquiterpene, named aquilarin B (1), together with two known compounds (2 and 3), was isolated from the EtOH extract of the fresh stem of Aquilaria sinensis (Lour.) Gilg. Their structures were elucidated by spectroscopic methods including 1D and 2D NMR (HMQC, H-1-H-1 COSY, HMBC, and ROESY). The cytotoxic activities of the three compounds against three human tumor cell lines K562, SMMC-7721, and SGC-7901 were evaluated, and compound 3 exhibited obvious cytotoxic activity.

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[1]Cucurbitacins from fruits of Aquilaria sinensis. Dai Hao-Fu. 2012

[2]2-(2-Phenylethyl)chromone Derivatives in Chinese Agarwood "Qi-Nan" from Aquilaria sinensis. Yang, De Lan,Mei, Wen Li,Zeng, Yan Bo,Guo, Zhi Kai,Zhao, You Xing,Wang, Hao,Zuo, Wen Jian,Dong, Wen Hua,Wang, Qing Huang,Dai, Hao Fu,Yang, De Lan,Mei, Wen Li,Zeng, Yan Bo,Guo, Zhi Kai,Zhao, You Xing,Wang, Hao,Zuo, Wen Jian,Dong, Wen Hua,Wang, Qing Huang,Dai, Hao Fu,Yang, De Lan. 2013

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