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Future trajectory of SARS-CoV-2: Constant spillover back and forth between humans and animals

文献类型： 外文期刊

作者： Cui, Xinhua 1 ; Wang, Yang 1 ; Zhai, Jingbo 3 ; Xue, Mengzhou 4 ; Zheng, Chunfu 2 ; Yu, Lu 1 ;

作者机构： 1.First Hosp Jilin Univ, Coll Vet Med, Ctr Infect Dis & Pathogen Biol, Dept Infect Dis,State Key Lab Human Anim Zoonot In, Changchun, Peoples R China

2.Guangdong Acad Agr Sci, Inst Anim Hlth, Key Lab Livestock Dis Prevent Guangdong Prov, Sci Observat & Expt Stn Vet Drugs & Diagnost Tech, Guangzhou, Peoples R China

3.Inner Mongolia Minzu Univ, Med Coll, Tongliao, Peoples R China

4.Zhengzhou Univ, Affiliated Hosp 2, Dept Cerebrovasc Dis, Zhengzhou, Peoples R China

5.Univ Calgary, Dept Microbiol Immunol & Infect Dis, Calgary, AB, Canada

6.Univ Inner Mongolia Autonomous Reg, Key Lab Zoonose Prevent & Control, Tongliao, Peoples R China

关键词： SARS-CoV-2; Zoonotic; Transmission; Spillover

期刊名称：VIRUS RESEARCH （ 影响因子：5.0； 五年影响因子：4.0 ）

ISSN： 0168-1702

年卷期： 2023 年 328 卷

页码：

收录情况： SCI

摘要： SARS-CoV-2, known as severe acute respiratory syndrome coronavirus 2, is causing a massive global public health dilemma. In particular, the outbreak of the Omicron variants of SARS-CoV-2 in several countries has aroused the great attention of the World Health Organization (WHO). As of February 1st, 2023, the WHO had counted 671,016,135 confirmed cases and 6,835,595 deaths worldwide. Despite effective vaccines and drug treatments, there is currently no way to completely and directly eliminate SARS-CoV-2. Moreover, frequent cases of SARS-CoV-2 infection in animals have also been reported. In this review, we suggest that SARS-CoV-2, as a zoonotic virus, may be frequently transmitted between animals and humans in the future, which provides a reference and warning for rational prevention and control of COVID-19.

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